What Do Microglia Really Do in Healthy Adult Brain?

Microglia originate from yolk sac-primitive macrophages and auto-proliferate into adulthood without replacement by bone marrow-derived circulating cells. In inflammation, stroke, aging, or infection, microglia have been shown to contribute to brain pathology in both deleterious and beneficial ways,...

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Bibliographic Details
Main Authors: Marcus Augusto-Oliveira, Gabriela P. Arrifano, Amanda Lopes-Araújo, Leticia Santos-Sacramento, Priscila Y. Takeda, Daniel C. Anthony, João O. Malva, Maria Elena Crespo-Lopez
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
cns
Online Access:https://www.mdpi.com/2073-4409/8/10/1293