The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos

Mitochondrial membrane Protein Associated Neurodegeneration (MPAN) is a rare genetic disorder due to mutations in C19orf12 gene. In most cases, the disorder is transmitted as an autosomal recessive trait and the main clinical features are progressive spastic para/tetraparesis, dystonia, motor axonal...

Full description

Bibliographic Details
Main Authors: Luca Mignani, Daniela Zizioli, Giuseppe Borsani, Eugenio Monti, Dario Finazzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.596069/full