TLR3/TAK1 signalling regulates rhinovirus-induced interleukin-33 in bronchial smooth muscle cells

Background Asthma exacerbations are commonly associated with rhinovirus (RV) infection. Interleukin-33 (IL-33) plays an important role during exacerbation by enhancing Type 2 inflammation. Recently we showed that RV infects bronchial smooth muscle cells (BSMCs) triggering production of interferons a...

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Bibliographic Details
Main Authors: Sangeetha Ramu, Jenny Calvén, Charalambos Michaeloudes, Mandy Menzel, Hamid Akbarshahi, Kian Fan Chung, Lena Uller
Format: Article
Language:English
Published: European Respiratory Society 2020-10-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/6/4/00147-2020.full