Statistical power of phylo-HMM for evolutionarily conserved element detection

<p>Abstract</p> <p>Background</p> <p>An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conserved elements based on multiple genome alignments, but the method...

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Bibliographic Details
Main Authors: Schadt Eric E, Zhu Jun, Fan Xiaodan, Liu Jun S
Format: Article
Language:English
Published: BMC 2007-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/8/374