How to Improve the Antioxidant Defense in Asphyxiated Newborns—Lessons from Animal Models

How to Improve the Antioxidant Defense in Asphyxiated Newborns—Lessons from Animal Models

Oxygen free radicals have been implicated in brain damage after neonatal asphyxia. In the early phase of asphyxia/reoxygenation, changes in antioxidant enzyme activity play a pivotal role in switching on and off the cascade of events that can kill the neurons. Hypoxia/ischemia (H/I) forces the brain...

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Bibliographic Details
Main Authors: Hanna Kletkiewicz, Maciej Klimiuk, Alina Woźniak, Celestyna Mila-Kierzenkowska, Karol Dokladny, Justyna Rogalska
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Antioxidants
Subjects:
neonatal hypoxia/ischemia
therapeutic hypothermia
deferoxamine
oxidative stress
antioxidants
neuroprotection
Online Access:https://www.mdpi.com/2076-3921/9/9/898

Internet

https://www.mdpi.com/2076-3921/9/9/898

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