Long-Term Lead Exposure Since Adolescence Causes Proteomic and Morphological Alterations in the Cerebellum Associated with Motor Deficits in Adult Rats

Long-Term Lead Exposure Since Adolescence Causes Proteomic and Morphological Alterations in the Cerebellum Associated with Motor Deficits in Adult Rats

Lead (Pb) is an environmental contaminant that presents a high risk for human health. We aimed to investigate the possible alterations triggered by the exposure to Pb acetate for a long period in motor performance and the possible relationship with biochemical, proteomic and morphological alteration...

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Bibliographic Details
Main Authors: Luana Ketlen Reis Leão, Leonardo Oliveira Bittencourt, Ana Carolina Oliveira, Priscila Cunha Nascimento, Giza Hellen Nonato Miranda, Railson Oliveira Ferreira, Mariane Nabiça, Kelly Dantas, Aline Dionizio, Sabrina Cartágenes, Marília Afonso Rabelo Buzalaf, Maria Elena Crespo-Lopez, Cristiane S F Maia, Rafael Rodrigues Lima
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
Lead
locomotion activity
morphological alterations
synaptic alteration
apoptosis
Online Access:https://www.mdpi.com/1422-0067/21/10/3571

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https://www.mdpi.com/1422-0067/21/10/3571

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