Human cellular immune response to the saliva of Phlebotomus papatasi is mediated by IL-10-producing CD8+ T cells and Th1-polarized CD4+ lymphocytes.

The saliva of sand flies strongly enhances the infectivity of Leishmania in mice. Additionally, pre-exposure to saliva can protect mice from disease progression probably through the induction of a cellular immune response.We analysed the cellular immune response against the saliva of Phlebotomus pap...

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Bibliographic Details
Main Authors: Maha Abdeladhim, Mélika Ben Ahmed, Soumaya Marzouki, Nadia Belhadj Hmida, Thouraya Boussoffara, Nabil Belhaj Hamida, Afif Ben Salah, Hechmi Louzir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3186761?pdf=render