Electroacupuncture attenuated cerebral ischemic injury and neuroinflammation through α7nAChR-mediated inhibition of NLRP3 inflammasome in stroke rats

Electroacupuncture attenuated cerebral ischemic injury and neuroinflammation through α7nAChR-mediated inhibition of NLRP3 inflammasome in stroke rats

Abstract Background Our previous research confirmed that electroacupuncture (EA) stimulus elicits neuroprotective effects against cerebral ischemic injury through α7 nicotinic acetylcholine receptor (α7nAChR)-mediated inhibition of high-mobility group box 1 release mechanism. This study investigated...

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Bibliographic Details
Main Authors: Tao Jiang, Meiyan Wu, Zhanqin Zhang, Chaoying Yan, Zhi Ma, Shan He, Wei Yuan, Kairui Pu, Qiang Wang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Medicine
Subjects:
Electroacupuncture
α7nAChR
NLRP3 inflammasome
Cerebral ischemia-reperfusion injury
Online Access:http://link.springer.com/article/10.1186/s10020-019-0091-4

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http://link.springer.com/article/10.1186/s10020-019-0091-4

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