An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model

An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model

Abstract Background Malaria remains the top infectious disease threat facing the U.S. military in many forward operating environments. Compliance with malaria chemoprophylaxis remains a critical component in preventing malaria in the deployed Service Member. Studies of previous military operations s...

Full description

Bibliographic Details
Main Authors: Jeffrey Livezey, Patrick Twomey, Meshell Morrison, Susan Cicatelli, Elizabeth H. Duncan, Melinda Hamer, Christine Lee, Jack Hutter, Kristin Mills, Jesse DeLuca, Lucas Poon, Daniel Selig, Chau Vuong, Jason Sousa, Thomas Oliver, Jason Bennett, James E. Moon, April Sikaffy, Martha Sedegah, Donna Tosh, Mara Kreishman-Deitrick, Paige Waterman
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Malaria Journal
Subjects:
Malaria chemoprophylaxis
Azithromycin
Chloroquine
Controlled human malaria infection
Online Access:http://link.springer.com/article/10.1186/s12936-020-03409-z

Internet

http://link.springer.com/article/10.1186/s12936-020-03409-z

Similar Items