Hypoxic microenvironment induced spatial transcriptome changes in pancreatic cancer

Hypoxic microenvironment induced spatial transcriptome changes in pancreatic cancer

Objective: Hypoxia is a significant feature of solid tumors, including pancreatic ductal adenocarcinoma (PDAC). It is associated with tumor invasion, metastasis, and drug resistance. However, the spatial distribution of hypoxia-related heterogeneity in PDAC remains unclear. Methods: Spatial transcri...

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Bibliographic Details
Main Authors: Huizhi Sun, Danfang Zhang, Chongbiao Huang, Yuhong Guo, Zhao Yang, Nan Yao, Xueyi Dong, Runfen Cheng, Nan Zhao, Jie Meng, Baocun Sun, Jihui Hao
Format: Article
Language:English
Published: China Anti-Cancer Association 2021-05-01
Series:Cancer Biology & Medicine
Subjects:
pancreatic cancer
hypoxia
spatial transcriptomic
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1864

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1864

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