Hypoxic microenvironment induced spatial transcriptome changes in pancreatic cancer
Objective: Hypoxia is a significant feature of solid tumors, including pancreatic ductal adenocarcinoma (PDAC). It is associated with tumor invasion, metastasis, and drug resistance. However, the spatial distribution of hypoxia-related heterogeneity in PDAC remains unclear. Methods: Spatial transcri...
Main Authors: | Huizhi Sun, Danfang Zhang, Chongbiao Huang, Yuhong Guo, Zhao Yang, Nan Yao, Xueyi Dong, Runfen Cheng, Nan Zhao, Jie Meng, Baocun Sun, Jihui Hao |
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Format: | Article |
Language: | English |
Published: |
China Anti-Cancer Association
2021-05-01
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Series: | Cancer Biology & Medicine |
Subjects: | |
Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/1864 |
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