Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts.

Clostridium difficile spores play a pivotal role in the transmission of infectious diarrhoea, but in order to cause disease spores must complete germination and return to vegetative cell growth. While the mechanisms of spore germination are well understood in Bacillus, knowledge of C. difficile germ...

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Bibliographic Details
Main Authors: Daniela Heeg, David A Burns, Stephen T Cartman, Nigel P Minton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3285209?pdf=render