Fusion of <it>EML4 </it>and <it>ALK </it>is associated with development of lung adenocarcinomas lacking <it>EGFR </it>and <it>KRAS </it>mutations and is correlated with ALK expression

<p>Abstract</p> <p>Background</p> <p>The anaplastic lymphoma kinase (<it>ALK</it>) gene is frequently involved in translocations that lead to gene fusions in a variety of human malignancies, including lymphoma and lung cancer. Fusion partners of <it>AL...

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Bibliographic Details
Main Authors: Zhang Xuchao, Zhang Shirley, Yang Xuening, Yang Jinji, Zhou Qing, Yin Lucy, An Shejuan, Lin Jiaying, Chen Shiliang, Xie Zhi, Zhu Mike, Zhang Xiaolin, Wu Yi-long
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/188