Bone marrow transplantation results in human donor blood cells acquiring and displaying mouse recipient class I MHC and CD45 antigens on their surface.

Bone marrow transplantation results in human donor blood cells acquiring and displaying mouse recipient class I MHC and CD45 antigens on their surface.

BACKGROUND: Mouse models of human disease are invaluable for determining the differentiation ability and functional capacity of stem cells. The best example is bone marrow transplants for studies of hematopoietic stem cells. For organ studies, the interpretation of the data can be difficult as trans...

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Bibliographic Details
Main Authors: Nobuko Yamanaka, Christine J Wong, Marina Gertsenstein, Robert F Casper, Andras Nagy, Ian M Rogers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2796175?pdf=render

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http://europepmc.org/articles/PMC2796175?pdf=render

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