Gene expression profiling in a mouse model identifies fetal liver- and placenta-derived potential biomarkers for Down Syndrome screening.

Gene expression profiling in a mouse model identifies fetal liver- and placenta-derived potential biomarkers for Down Syndrome screening.

BACKGROUND: As a first step to identify novel potential biomarkers for prenatal Down Syndrome screening, we analyzed gene expression in embryos of wild type mice and the Down Syndrome model Ts1Cje. Since current Down Syndrome screening markers are derived from placenta and fetal liver, these tissues...

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Bibliographic Details
Main Authors: Jeroen L A Pennings, Wendy Rodenburg, Sandra Imholz, Maria P H Koster, Conny T M van Oostrom, Timo M Breit, Peter C J I Schielen, Annemieke de Vries
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3077415?pdf=render

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http://europepmc.org/articles/PMC3077415?pdf=render

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