Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma.

It has been hypothesized that synaptic pruning precedes retinal ganglion cell degeneration in glaucoma, causing early dysfunction to retinal ganglion cells. To begin to assess this, we studied the excitatory synaptic inputs to individual ganglion cells in normal mouse retinas and in retinas with gan...

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Bibliographic Details
Main Authors: Ryan H Berry, Juan Qu, Simon W M John, Gareth R Howell, Tatjana C Jakobs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4670161?pdf=render