Biochemical distribution of tau protein in synaptosomal fraction of transgenic mice expressing human P301L tau

Biochemical distribution of tau protein in synaptosomal fraction of transgenic mice expressing human P301L tau

Alzheimer’s disease is a progressive dementia that is characterized by a loss of recent memory. Evidence has accumulated to support the hypothesis that synapses are critical storage sites for memory. However, it is still uncertain whether tau protein is involved in associative memory storage and whe...

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Bibliographic Details
Main Authors: Naruhiko eSahara, Miyuki eMurayama, Makoto eHiguchi, Suhara eTetsuya, Akihiko eTakashima
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Neurology
Subjects:
Subcellular Fractions
Transgenic mice
Tau phosphorylation
P301L tau
synaptosomal fraction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00026/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00026/full

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