Transcriptome dynamics during cholesterol-induced transdifferentiation of human coronary artery smooth muscle cells: A Gene Ontology-centric clustering approach

Transcriptome dynamics during cholesterol-induced transdifferentiation of human coronary artery smooth muscle cells: A Gene Ontology-centric clustering approach

Macrophage-like cells derived from vascular smooth muscle cells (SMCs) play critical roles in atherogenesis, and DNA hydroxymethylation was implicated in transdifferentiation. We examined transcriptomes and (hydroxy)methylomes of human coronary artery SMCs during cholesterol-induced transdifferentia...

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Bibliographic Details
Main Authors: Kentaro Inoue, Hiromitsu Araki, Fumihito Miura, Takashi Ito
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Smooth muscle cell
Cholesterol
Epigenetics
Inflammation
Dedifferentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821001552

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http://www.sciencedirect.com/science/article/pii/S2405580821001552

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