Methylsulfonylmethane suppresses breast cancer growth by down-regulating STAT3 and STAT5b pathways.

Breast cancer is the most aggressive form of all cancers, with high incidence and mortality rates. The purpose of the present study was to investigate the molecular mechanism by which methylsulfonylmethane (MSM) inhibits breast cancer growth in mice xenografts. MSM is an organic sulfur-containing na...

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Bibliographic Details
Main Authors: Eun Joung Lim, Dae Young Hong, Jin Hee Park, Youn Hee Joung, Pramod Darvin, Sang Yoon Kim, Yoon Mi Na, Tae Sook Hwang, Sang-Kyu Ye, Eon-Soo Moon, Byung Wook Cho, Kyung Do Park, Hak Kyo Lee, Taekyu Park, Young Mok Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3317666?pdf=render