Alteration in Marrow Stromal Microenvironment and Apoptosis Mechanisms Involved in Aplastic Anemia: An Animal Model to Study the Possible Disease Pathology

Aplastic anemia (AA) is a heterogeneous disorder of bone marrow failure syndrome. Suggested mechanisms include a primary stem cell deficiency or defect, a secondary stem cell defect due to abnormal regulation between cell death and differentiation, or a deficient microenvironment. In this study, we...

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Bibliographic Details
Main Authors: Sumanta Chatterjee, Ranjan Kumar Dutta, Pratima Basak, Prosun Das, Madhurima Das, Jacintha Archana Pereira, Malay Chaklader, Samaresh Chaudhuri, Sujata Law
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.4061/2010/932354