Treatment of Chronic Venous Ulcers With Heterologous Fibrin Sealant: A Phase I/II Clinical Trial

Treatment of Chronic Venous Ulcers With Heterologous Fibrin Sealant: A Phase I/II Clinical Trial

BackgroundHeterologous fibrin sealant (HFS) consists of a fibrinogen-rich cryoprecipitate extracted from Bubalus bubalis buffalo blood and a thrombin-like enzyme purified from Crotalus durissus terrificus snake venom. This study evaluated the safety and immunogenicity of HFS, estimated the best dose...

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Bibliographic Details
Main Authors: Luciana P. F. Abbade, Silvia Regina Catharino Sartori Barraviera, Maria Regina Cavariani Silvares, Ana Beatriz B. de C. O. Lima, Gabriela R. Haddad, Márcia A. N. Gatti, Natália Bronzatto Medolago, Márcia Tonin Rigotto Carneiro, Lucilene Delazari dos Santos, Rui Seabra Ferreira, Benedito Barraviera
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
varicose ulcer
biological dressings
fibrin tissue adhesive
fibrin glue
fibrin sealant
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.627541/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.627541/full

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