An in vitro model for dengue virus infection that exhibits human monocyte infection, multiple cytokine production and dexamethasone immunomodulation

An in vitro model for dengue virus infection that exhibits human monocyte infection, multiple cytokine production and dexamethasone immunomodulation

An important cytokine role in dengue fever pathogenesis has been described. These molecules can be associated with haemorrhagic manifestations, coagulation disorders, hypotension and shock, all symptoms implicated in vascular permeability and disease worsening conditions. Several immunological disea...

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Bibliographic Details
Main Authors: Sônia Regina Nogueira Ignácio Reis, André Luiz Franco Sampaio, Maria das Graças Muller Henriques, Mariana Gandini, Elzinandes Leal Azeredo, Claire Fernandes Kubelka
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2007-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
dengue
dexamethasone
monocytes
cytokines
therapeutics
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000800014

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000800014

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