Progesterone, but not β-estradiol, enhances Porphyromonas gingivalis lipopolysaccharide-induced vascular endothelial growth factor-A expression in human THP-1 monocytes

Background/purpose: Progesterone and estrogen levels are elevated during pregnancy and play a role in maternal immune responses. In addition, unbalanced metabolism of growth factors has been demonstrated in pregnancy tumors. Therefore, we aimed to investigate the effect of progesterone and β-estradi...

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Bibliographic Details
Main Authors: Paiboon Jitprasertwong, Niratcha Chaisomboon, Kusuma Jamdee
Format: Article
Language:English
Published: Elsevier 2013-12-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790213001359