Melatonin receptor stimulation by agomelatine prevents Aβ-induced tau phosphorylation and oxidative damage in PC12 cells

Kai Yao, Yong-fei Zhao, Heng-bing Zu Department of Neurology, Jinshan Hospital Affiliated to Fudan University, Shanghai 201508, China Purpose: As a novel antidepressant drug, agomelatine has good therapeutic effect on the mood disorder and insomnia in Alzheimer’s disease (AD). Recent stu...

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Bibliographic Details
Main Authors: Yao K, Zhao Y, Zu H
Format: Article
Language:English
Published: Dove Medical Press 2019-01-01
Series:Drug Design, Development and Therapy
Subjects:
Online Access:https://www.dovepress.com/melatonin-receptor-stimulation-by-agomelatine-prevents-abeta-induced-t-peer-reviewed-article-DDDT