Concordant changes of plasma and kidney microRNA in the early stages of acute kidney injury: time course in a mouse model of bilateral renal ischemia-reperfusion.

BACKGROUND: Acute kidney injury (AKI) is a syndrome characterized by the rapid loss of the kidney excretory function and is strongly associated with increased early and long-term patient morbidity and mortality. Early diagnosis of AKI is challenging; therefore we profiled plasma microRNA in an effor...

Full description

Bibliographic Details
Main Authors: Melissa A Bellinger, James S Bean, Melissa A Rader, Kathleen M Heinz-Taheny, Jairo S Nunes, Joseph V Haas, Laura F Michael, Mark D Rekhter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3973691?pdf=render