Reliable cell cycle commitment in budding yeast is ensured by signal integration
Cell fate decisions are critical for life, yet little is known about how their reliability is achieved when signals are noisy and fluctuating with time. In this study, we show that in budding yeast, the decision of cell cycle commitment (Start) is determined by the time integration of its triggering...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/03977 |