Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor
The melanocortin-4 receptor (MC4R) is a class A G protein-coupled receptor (GPCR), essential for regulation of appetite and metabolism. Pathogenic inactivating <i>MC4R</i> mutations are the most frequent cause of monogenic obesity, a growing medical and socioeconomic problem worldwide. T...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-08-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/21/16/5728 |