Serum Protein N-Glycosylation Changes with Rheumatoid Arthritis Disease Activity during and after Pregnancy

Serum Protein N-Glycosylation Changes with Rheumatoid Arthritis Disease Activity during and after Pregnancy

Symptoms of rheumatoid arthritis (RA) improve during pregnancy, a phenomenon that was found to be associated with N-glycosylation changes of immunoglobulin G. Recent advances in high-throughput glycosylation analysis allow the assessment of the N-glycome of human sera as well. The aim of this study...

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Bibliographic Details
Main Authors: Karli R. Reiding, Gerda C. M. Vreeker, Albert Bondt, Marco R. Bladergroen, Johanna M. W. Hazes, Yuri E. M. van der Burgt, Manfred Wuhrer, Radboud J. E. M. Dolhain
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Medicine
Subjects:
rheumatoid arthritis
pregnancy
disease activity score 28 C-reactive protein
glycosylation
total serum protein N-glycosylation
ethyl esterification matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00241/full

Internet

http://journal.frontiersin.org/article/10.3389/fmed.2017.00241/full

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