Hydroxypropyl-Beta-Cyclodextrin Reduces Inflammatory Signaling from Monocytes: Possible Implications for Suppression of HIV Chronic Immune Activation

Hydroxypropyl-Beta-Cyclodextrin Reduces Inflammatory Signaling from Monocytes: Possible Implications for Suppression of HIV Chronic Immune Activation

Chronic immune activation is a hallmark of HIV infection and is often not controlled even in patients under antiretroviral therapy. Indeed, chronic diseases with inflammatory pathogenesis are being reported as major causes of death for HIV-infected persons. Hydroxypropyl-beta cyclodextrin (HP-BCD) i...

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Bibliographic Details
Main Authors: Flávio Lemos Matassoli, Ihid Carneiro Leão, Bruno Braz Bezerra, Richard B. Pollard, Dieter Lütjohann, James E. K. Hildreth, Luciana Barros de Arruda
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mSphere
Subjects:
HIV
beta-cyclodextrin
monocytes
inflammation
human immunodeficiency virus
Online Access:https://doi.org/10.1128/mSphere.00497-18

Internet

https://doi.org/10.1128/mSphere.00497-18

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