The Evolutionary Conserved Transmembrane BAX Inhibitor Motif (TMBIM) Containing Protein Family Members 5 and 6 Are Essential for the Development and Survival of Drosophila melanogaster

The Evolutionary Conserved Transmembrane BAX Inhibitor Motif (TMBIM) Containing Protein Family Members 5 and 6 Are Essential for the Development and Survival of Drosophila melanogaster

The mammalian Transmembrane BAX Inhibitor Motif (TMBIM) protein family consists of six evolutionarily conserved hydrophobic proteins that affect programmed cell death and the regulation of intracellular calcium levels. The bacterial ortholog BsYetJ is a pH-dependent calcium channel. We here identifi...

Full description

Bibliographic Details
Main Authors: Li Zhang, Sebastian Buhr, Aaron Voigt, Axel Methner
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
calcium
mitochondria
ER stress
GRINA
lifeguard
MICS1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.666484/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.666484/full

Similar Items