Leukotriene D4 Stimulates the Migration but Not Proliferation of Endothelial Cells Mediated by the Cysteinyl Leukotriene CysLT1 Receptor via the Extracellular Signal-Regulated Kinase Pathway

The actions of cysteinyl leukotrienes (CysLTs) are mediated by activating CysLT receptors, CysLT1, and CysLT2. The CysLT1 receptor mediates vascular responses to CysLTs; however, its effect on the proliferation and migration of endothelial cells is not clarified. To determine this effect, we observe...

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Bibliographic Details
Main Authors: Yu-Mei Yuan, San-Hua Fang, Xiao-Dong Qian, Li-Ying Liu, Li-Hua Xu, Wen-Zhen Shi, Li-Hui Zhang, Yun-Bi Lu, Wei-Ping Zhang, Er-Qing Wei
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319312848