Thermogenic Activation Downregulates High Mitophagy Rate in Human Masked and Mature Beige Adipocytes

Thermogenic Activation Downregulates High Mitophagy Rate in Human Masked and Mature Beige Adipocytes

Thermogenic brown and beige adipocytes oxidize metabolic substrates producing heat, mainly by the mitochondrial uncoupling protein UCP1, and can thus counteract obesity. Masked beige adipocytes possess white adipocyte-like morphology, but can be made thermogenic by adrenergic stimuli. We investigate...

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Bibliographic Details
Main Authors: Mária Szatmári-Tóth, Abhirup Shaw, István Csomós, Gábor Mocsár, Pamela Fischer-Posovszky, Martin Wabitsch, Zoltán Balajthy, Cecília Lányi, Ferenc Győry, Endre Kristóf, László Fésüs
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
beige adipocytes
UCP1
mitophagy
LC3
cAMP
Parkin
Online Access:https://www.mdpi.com/1422-0067/21/18/6640

Internet

https://www.mdpi.com/1422-0067/21/18/6640

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