A <i>PDCD1</i> Role in the Genetic Predisposition to NAFLD-HCC?

A <i>PDCD1</i> Role in the Genetic Predisposition to NAFLD-HCC?

Obesity and non-alcoholic fatty liver disease (NAFLD) are contributing to the global rise in deaths from hepatocellular carcinoma (HCC). The pathogenesis of NAFLD-HCC is not well understood. The severity of hepatic steatosis, steatohepatitis and fibrosis are key pathogenic mechanisms, but animal stu...

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Bibliographic Details
Main Authors: Nardeen Eldafashi, Rebecca Darlay, Ruchi Shukla, Misti Vanette McCain, Robyn Watson, Yang Lin Liu, Nikki McStraw, Moustafa Fathy, Michael Atef Fawzy, Marco Y. W. Zaki, Ann K. Daly, João P. Maurício, Alastair D. Burt, Beate Haugk, Heather J. Cordell, Cristiana Bianco, Jean-François Dufour, Luca Valenti, Quentin M. Anstee, Helen L. Reeves
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
primary liver cancer
hepatocellular carcinoma
metabolic syndrome
genetic predisposition
single-nucleotide polymorphism
<i>PDCD1</i>
Online Access:https://www.mdpi.com/2072-6694/13/6/1412

Internet

https://www.mdpi.com/2072-6694/13/6/1412

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