Inspiratory Efforts, Positive End-Expiratory Pressure, and External Resistances Influence Intraparenchymal Gas Redistribution in Mechanically Ventilated Injured Lungs

Inspiratory Efforts, Positive End-Expiratory Pressure, and External Resistances Influence Intraparenchymal Gas Redistribution in Mechanically Ventilated Injured Lungs

BackgroundPotentially harmful lung overstretch can follow intraparenchymal gas redistribution during mechanical ventilation. We hypothesized that inspiratory efforts characterizing spontaneous breathing, positive end-expiratory pressure (PEEP), and high inspiratory resistances influence inspiratory...

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Bibliographic Details
Main Authors: Mariangela Pellegrini, Göran Hedenstierna, Anders Sune Larsson, Gaetano Perchiazzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Physiology
Subjects:
assisted mechanical ventilation
lung heterogeneity
mild acute respiratory distress syndrome
CT imaging
self-induced lung injury
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.618640/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.618640/full

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