Versican and Tumor-Associated Macrophages Promotes Tumor Progression and Metastasis in Canine and Murine Models of Breast Carcinoma

Versican and tumor-associated macrophages (TAMs) are involved in growth and metastases in several cancers. Here, we investigated the potential role of versican, a matrix proteoglycan, and its correlation with TAMs infiltrates in different stages of two different breast cancer models: spontaneous can...

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Bibliographic Details
Main Authors: Diego Carlos dos Reis, Karine Araújo Damasceno, Cecília Bonolo de Campos, Emerson Soares Veloso, Gabriela Rafaela Arantes Pêgas, Lucas Rocha Kraemer, Michele Angela Rodrigues, Matheus Silvério Mattos, Dawidson Assis Gomes, Paula Peixoto Campos, Enio Ferreira, Remo Castro Russo, Geovanni Dantas Cassali
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00577/full