The proteasome activity reporter GFP-Cl1 is degraded by autophagy in the aging model Podospora anserina [v1; ref status: indexed, http://f1000r.es/4e9]

The degradation of damaged proteins is an important vital function especially during aging and stress. The ubiquitin proteasome system is one of the major cellular machineries for protein degradation. Health and longevity are associated with high proteasome activity. To demonstrate such a role in ag...

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Bibliographic Details
Main Authors: Matthias Wiemer, Heinz D. Osiewacz
Format: Article
Language:English
Published: F1000 Research Ltd 2014-09-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/3-230/v1