PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis.

PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis.

Both genetic and environmental factors are associated with susceptibility to juvenile idiopathic arthritis (JIA). Many studies have reported that both a 'shared epitope' (SE) encoded by several HLA-DRB1 alleles and the peptidyl arginine deiminase type 4 (PADI4) gene polymorphisms are assoc...

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Bibliographic Details
Main Authors: Kaori Hisa, Masakatsu D Yanagimachi, Takuya Naruto, Takako Miyamae, Masako Kikuchi, Rhoki Hara, Tomoyuki Imagawa, Shumpei Yokota, Masaaki Mori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5300194?pdf=render

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http://europepmc.org/articles/PMC5300194?pdf=render

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