A convenient method for the synthesis of (prop-2-ynyloxy)benzene derivatives via reaction with propargyl bromide, their optimization, scope and biological evaluation.

A highly convenient method has been developed for the synthesis of (prop-2-ynyloxy) benzene and its derivatives. Differently substituted phenol and aniline derivatives were allowed to react with propargyl bromide in the presence of K2CO3 base and acetone as solvent. The compounds were synthesized in...

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Bibliographic Details
Main Authors: Tannaza Batool, Nasir Rasool, Yasmeen Gull, Mnaza Noreen, Faiz-ul-Hassan Nasim, Asma Yaqoob, Muhammad Zubair, Usman Ali Rana, Salah Ud-Din Khan, M Zia-Ul-Haq, Hawa Z E Jaafar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4278708?pdf=render