Efficiency of different strategies to mitigate ascertainment bias when using SNP panels in diversity studies

Efficiency of different strategies to mitigate ascertainment bias when using SNP panels in diversity studies

Abstract Background Single nucleotide polymorphism (SNP) panels have been widely used to study genomic variations within and between populations. Methods of SNP discovery have been a matter of debate for their potential of introducing ascertainment bias, and genetic diversity results obtained from t...

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Bibliographic Details
Main Authors: Dorcus Kholofelo Malomane, Christian Reimer, Steffen Weigend, Annett Weigend, Ahmad Reza Sharifi, Henner Simianer
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Genomics
Subjects:
SNP filtering
Ascertainment bias
LD based pruning
SNP panels
Online Access:http://link.springer.com/article/10.1186/s12864-017-4416-9

Internet

http://link.springer.com/article/10.1186/s12864-017-4416-9

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