Identification of Novel Candidate CD8<sup>+</sup> T Cell Epitopes of the SARS-CoV2 with Homology to Other Seasonal Coronaviruses

Identification of Novel Candidate CD8<sup>+</sup> T Cell Epitopes of the SARS-CoV2 with Homology to Other Seasonal Coronaviruses

Cross-reactive T cell immunity to seasonal coronaviruses (HCoVs) may lead to immunopathology or protection during SARS-CoV2 infection. To understand the influence of cross-reactive T cell responses, we used IEDB (Immune epitope database) and NetMHCpan (ver. 4.1) to identify candidate CD8<sup>+...

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Bibliographic Details
Main Authors: Pradeep Darshana Pushpakumara, Deshan Madhusanka, Saubhagya Dhanasekara, Chandima Jeewandara, Graham S. Ogg, Gathsaurie Neelika Malavige
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
CD8<sup>+</sup> T cell epitopes
SARS-CoV2
seasonal coronaviruses
HLA alleles
OC-43
HKU-1
Online Access:https://www.mdpi.com/1999-4915/13/6/972

Internet

https://www.mdpi.com/1999-4915/13/6/972

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