Mitosis gives a brief window of opportunity for a change in gene transcription.
Cell differentiation is remarkably stable but can be reversed by somatic cell nuclear transfer, cell fusion, and iPS. Nuclear transfer to amphibian oocytes provides a special opportunity to test transcriptional reprogramming without cell division. We show here that, after nuclear transfer to amphibi...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-07-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC4114836?pdf=render |