Neuroprotective Effect of α-Mangostin in the Ameliorating Propionic Acid-Induced Experimental Model of Autism in Wistar Rats

Neuroprotective Effect of α-Mangostin in the Ameliorating Propionic Acid-Induced Experimental Model of Autism in Wistar Rats

Several studies have documented the role of hyper-activation of extracellular signal-regulated kinases (ERK) in Autism pathogenesis. Alpha-mangostin (AMG) is a phytoconstituents with anti-oxidants, anti-inflammatory, and ERK inhibition properties in many diseases. Our research aims to investigate th...

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Bibliographic Details
Main Authors: Aarti Tiwari, Rishabh Khera, Saloni Rahi, Sidharth Mehan, Hafiz Antar Makeen, Yahya H. Khormi, Muneeb U Rehman, Andleeb Khan
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Brain Sciences
Subjects:
Autism spectrum disorder
ERK/mitogen activated protein kinase (MAPK)
α-mangostin
propionic acid
neuroexcitation
genetic dysfunction
Online Access:https://www.mdpi.com/2076-3425/11/3/288

Internet

https://www.mdpi.com/2076-3425/11/3/288

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