Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification.

Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification.

End-stage renal disease is strongly associated with progressive cardiovascular calcification (CVC) and there is currently no therapy targeted to treat CVC. SNF472 is an experimental formulation under development for treatment of soft tissue calcification. We have investigated the pharmacokinetics of...

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Bibliographic Details
Main Authors: Miguel D Ferrer, Markus Ketteler, Fernando Tur, Eva Tur, Bernat Isern, Carolina Salcedo, Pieter H Joubert, Geert J Behets, Ellen Neven, Patrick C D'Haese, Joan Perelló
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5942814?pdf=render

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http://europepmc.org/articles/PMC5942814?pdf=render

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