Amphiregulin impairs apoptosis-stimulating protein 2 of p53 overexpression–induced apoptosis in hepatoma cells
Overexpression of apoptosis-stimulating protein 2 of p53 (ASPP2) induces apoptotic cell death in hepatoma cells (e.g. HepG2 cells) by enhancing the transactivation activity of p53, but long-term ASPP2 overexpression fails to induce more apoptosis since activation of the epidermal growth factor/epide...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-03-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317695026 |