Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice

Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice

Abstract Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that oestrogen receptors (ERs) play a major role in postmenopausal obesity and depression. However, little is known regarding the ER subtype...

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Bibliographic Details
Main Authors: Daimei Sasayama, Nobuhiro Sugiyama, Shigeru Yonekubo, Akiko Pawlak, Hiroyasu Murasawa, Mie Nakamura, Morimichi Hayashi, Takashi Ogawa, Makoto Moro, Shinsuke Washizuka, Naoji Amano, Kazuhiro Hongo, Hideki Ohnota
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04946-5

Internet

https://doi.org/10.1038/s41598-017-04946-5

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