Comparing Oprm1 Gene Promoter Methylation in the Lymphocytes of Male Rats Addicted to Nicotine, Morphine, Methadone, and Buprenorphine

Comparing Oprm1 Gene Promoter Methylation in the Lymphocytes of Male Rats Addicted to Nicotine, Morphine, Methadone, and Buprenorphine

Background: Addiction is a polygenic disorder caused by genetic and environmental factors. The opioid material can act as an epigenetic element, like DNA methylation.  Objectives: The present study aimed to examine the effect of epigenetic drugs such as nicotine, morphine, methadone, and buprenorphi...

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Bibliographic Details
Main Authors: Maedeh Mohammad Alizadeh, Seyed Reza Kazemi Nezhad, Parvin Babaei, Parvaneh Keshavarz
Format: Article
Language:English
Published: Guilan University of Medical Sciences 2019-11-01
Series:Caspian Journal of Neurological Sciences
Subjects:
nicotine
morphine
methadone
buprenorphine
dna methylation
Online Access:http://cjns.gums.ac.ir/article-1-294-en.html

Internet

http://cjns.gums.ac.ir/article-1-294-en.html

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