A Flow Cytometry-Based Whole Blood Natural Killer Cell Cytotoxicity Assay Using Overnight Cytokine Activation

A Flow Cytometry-Based Whole Blood Natural Killer Cell Cytotoxicity Assay Using Overnight Cytokine Activation

Background: Measurement of natural killer (NK) cell function has important clinical utility in several diseases. Although the flow cytometry (FC)-based 4-h NK cytotoxicity assay using peripheral blood mononuclear cells (PBMCs) in the clinical laboratory has been used for this purpose, this assay req...

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Bibliographic Details
Main Authors: Jinho Kim, Minh-Trang Thi Phan, SoonHo Kweon, HongBi Yu, Jeehun Park, Kyeong-Hee Kim, Ilwoong Hwang, Sangbin Han, Min-Jung Kwon, Duck Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
activity assay
cytotoxicity
whole blood
cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01851/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01851/full

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