Plastrum Testudinis Extracts Promote BMSC Proliferation and Osteogenic Differentiation by Regulating Let-7f-5p and the TNFR2/PI3K/AKT Signaling Pathway

Plastrum Testudinis Extracts Promote BMSC Proliferation and Osteogenic Differentiation by Regulating Let-7f-5p and the TNFR2/PI3K/AKT Signaling Pathway

Background/Aims: Plastrum testudinis extracts (PTE) show osteoprotective effects on glucocorticoid-induced osteoporosis in vivo and in vitro. However, the underlying molecular mechanism of PTE in promoting osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is unclear. Methods:...

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Bibliographic Details
Main Authors: Geng-Yang Shen, Hui Ren, Jin-Jing Huang, Zhi-Da Zhang, Wen-Hua Zhao, Xiang Yu, Qi Shang, Ting Qiu, Yu-Zhuo Zhang, Jing-Jing Tang, De Liang, Zhi-Dong Yang, Xiao-bing Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Proliferation
Osteogenic differentiation
Pte
Let-7f-5p
TNFR2/PI3K/AKT signaling pathway
BMSCs
Online Access:https://www.karger.com/Article/FullText/491541

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https://www.karger.com/Article/FullText/491541

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