Single-pulse stimulation of cerebellar nuclei stops epileptic thalamic activity

Single-pulse stimulation of cerebellar nuclei stops epileptic thalamic activity

Background: Epileptic (absence) seizures in the cerebral cortex can be stopped by pharmacological and optogenetic stimulation of the cerebellar nuclei (CN) neurons that innervate the thalamus. However, it is unclear how such stimulation can modify underlying thalamo-cortical oscillations. Hypothesis...

Full description

Bibliographic Details
Main Authors: Oscar H.J. Eelkman Rooda, Lieke Kros, Sade J. Faneyte, Peter J. Holland, Simona V. Gornati, Huub J. Poelman, Nico A. Jansen, Else A. Tolner, Arn M.J.M. van den Maagdenberg, Chris I. De Zeeuw, Freek E. Hoebeek
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Brain Stimulation
Subjects:
Cerebellum
Generalized absence seizures
Optogenetic neurostimulation
Thalamus
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X21001005

Internet

http://www.sciencedirect.com/science/article/pii/S1935861X21001005

Similar Items