Role of Pre-molten Globule Structure in Protein Amyloid Fibril Formation

The conversion of a protein from its native conformation to the pathogenic form is a critical event in the pathogenesis of several neurodegenerative disorders such as Alzheimer’s (AD), Parkinson’s, and Huntington’s diseases, along with type II diabetic mellitus. Although there are several reports on...

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Bibliographic Details
Main Authors: Ali Es-haghi, Mahsa Jahedi Moghaddam, Koorosh Shahpasand
Format: Article
Language:English
Published: Hamadan University of Medical Sciences 2019-06-01
Series:Avicenna Journal of Medical Biochemistry
Subjects:
Online Access:http://ajmb.umsha.ac.ir/PDF/ajmb-2149